I also found a part in the Doctor Who story that is very similar to the bomb and the submarine in Lost. The Jewel in question had an explosive type quality to it. The Guardians and Amy play out the part of Sayid in detonating the bomb.
Excerpt from the Destroyer of Delights:
The Doctor leads the others to the airlock, but they discover the Djinni must have overridden the codes and the password is no longer working. The Guardians start to panic and the Doctor realises they’re now prisoners of these dimensions and will die like everyone else if they don’t get off the ship. The Doctor finds another jewel like the one in the necklace, and tells Guardians to take it down to the far end of the spaceship while he prepares to fire the projectile guns. With any luck, it’ll blow a hole in the hull.
The two Guardians head for the front of the ship and come across another room filled with treasures taken from other worlds. The White Guardian points out that if the Black Guardian had given just part of this to the Caliph instead of the gold, there would have been no trouble. Unfortunately these are the private quarters of the Djinni and the Black Guardian had never been to this part of the ship before. They throw down the tracker and then run for their lives. The Doctor powers up the guns and Amy asks if she can press the button. She does so and the projectile fires straight up into the air, then turns and heads back down towards them. There’s a massive explosion and the ship is filled with smoke and debris. The Guardians pick themselves up of the floor and discover the front of the ship is now exposed to the desert, exactly as the Doctor had intended.